Histone Chaperones: Modulators of Chromatin Marks
نویسندگان
چکیده
منابع مشابه
Histone Chaperones in the Assembly and Disassembly of Chromatin
Nucleosomes physically block access to the DNA, raising several questions (1) How are new nucleosomes formed in vivo? (2) How are nucleosomes removed to facilitate DNA templated processes? and (3) How are histones restored to the DNA following the completion of those processes? The intrinsic attraction between the negatively charged DNA phosphate backbone and the positively charged lysine and a...
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The eukaryotic processes of nucleosome assembly and disassembly govern chromatin dynamics, in which histones exchange in a highly regulated manner to promote genome accessibility for all DNA-dependent processes. This regulation is partly carried out by histone chaperones, which serve multifaceted roles in co-ordinating the interactions of histone proteins with modification enzymes, nucleosome r...
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ژورنال
عنوان ژورنال: Molecular Cell
سال: 2011
ISSN: 1097-2765
DOI: 10.1016/j.molcel.2011.02.013